Dog - Mitotane

Why has my veterinary surgeon prescribed this medicine?

Mitotane is used for treating Cushing's syndrome. Mitotane reduces the amount of cortisone like hormones produced by the adrenal cortex. These steroids are important for various body functions, however too much hormone can cause problems.

Mitotane is not readily available in the UK. Your veterinary surgeon will have to apply for a special request to obtain a supply to treat your pet.

How do I give this medication?

• Give this medication to your pet as directed by your veterinary surgeon. READ THE LABEL CAREFULLY.
• Give this medication with food.
• Try to give this medication at about the same time(s) each day and try not to miss giving any doses.
• DO NOT give the pet more medicine than directed and DO NOT give more often than directed.
• DO NOT stop giving this medication to your pet unless directed by your veterinary surgeon. Contact your veterinary surgeon in advance if your pet needs a further prescription.
• Wear disposable gloves when handling the medication and wash your hands afterwards.
• In case of accidental ingestion, seek medical advice immediately and show the package leaflet or label to the physician.

What if I miss giving a dose?

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give the pet two doses at once.

How do I store this medicine?

Keep this medicine out of reach of children. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.

Potential side effects

• Your pet may experience the following side effects: diarrhoea, sedation, weakness, vomiting and loss of appetite. Contact your veterinary surgeon if these symptoms persist or are troublesome.
• Notify your veterinary surgeon if your pet experiences neurological signs (i.e. incoordination, blindness, facial paralysis and seizures). Other side effects may occur. If you notice anything unusual, contact your veterinary surgeon.

Possible drug interactions

• Make sure to tell your veterinary surgeon what other medication you are giving to your pet.
• Quite often your veterinary surgeon may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinary surgeon may vary the dose and/or monitor your pet more closely.
• Contact your veterinary surgeon if your pet experiences any unusual reactions when different medications are given together.