Cat & Dog - MSM

What is MSM?

MSM (methylsulfonylmethane) also known as dimethylsulfone. DMSO2 is a sulphur bearing compound that exists naturally in cows' milk (its highest source), many fruits, grains and meat. It is a natural anti-inflammatory and analgesic (pain killing) product. It is produced when DMSO (dimethylsulfoxide) is oxidised, and although research is extensive on DMSO, research on MSM has been more limited. A wide range of therapeutic benefits as well as a high degree of safety makes it a popular supplement, although research is sparse.

MSM is a source of sulphur, the fourth most common mineral in the body. Sulphur is involved in many processes including nerve signal transmission, enzyme processes, insulin production, detoxification processes and carbohydrate metabolism. MSM also provides a sulphur source for the synthesis of methionine by intestinal microbes. It also appears to be a precursor molecule for cysteine synthesis.

MSM as a source of sulphur is reported to be useful in degenerative disorders, musculoskeletal, respiratory (lung), eliminative, circulatory and auto-immune conditions. It is also used in humans to treat many of the same conditions as the methionine derivative SAMe (S-adenosylmethionine), including pain, inflammation, allergies, arthritis, and the maintenance of normal keratin levels in hair, skin and nails.

An emerging application of MSM is in the induction of cancer cell differentiation. MSM compares favourably to low doses of aspirin in its ability to promote the aging of tumour cells to the point that limits are placed on their lifespan and the number of times they are permitted to multiply. The net effect of cell differentiating agents is to slow the growth or even shrink tumours, as cancer cells begin to die off and are less rapidly replaced.

How much experience is there with the use of MSM in pets?

MSM has been used for several years in the treatment of arthritis in pets.

What species of animals are being treated regularly with MSM?

Dogs are the main species treated; cats may also benefit.

How much research has been conducted on this supplement?

Clinical trials of MSM are limited. A clinically significant effect was observed on respiratory tract inflammation and function in humans. Clinical outcomes in animals receiving MSM for osteoarthritis are also encouraging.

How safe is MSM?

MSM is considered non-toxic. However, it does have mild blood thinning effects, therefore caution should be taken when administering with other potentially blood thinning agents such as fish oil. Side effects can include diarrhoea, thicker nails, softer skin and stiffer hair. On the other hand some of these signs of ‘stress’ can be improved with MSM.

Where do I obtain MSM and do I need a prescription?

Please see one of the vets if you would like to discuss the use of an MSM product in your pet. A prescription is not required.